发明名称 |
A METHOD AND COMPOSITION FOR REGULATING SERUM CALCIUM LEVELS OF MAMMALS |
摘要 |
Method for regulating serum cacium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormon is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed. |
申请公布号 |
WO8700750(A1) |
申请公布日期 |
1987.02.12 |
申请号 |
WO1986US01553 |
申请日期 |
1986.07.25 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
HOSTETLER, KARL, Y.;DEFTOS, LEONARD, J. |
分类号 |
A61K38/00;A61K9/10;A61K9/127;A61K38/23;A61K38/29;(IPC1-7):A61K9/10;A61K37/30 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|