发明名称 CARBOXY,CARBOALKOXY AND CARBAMYL SUBSTITUTED ISONITRILE RADIONUCLIDE COMPLEXES
摘要 A coordination complex comprising a radionuclide selected from the class consisting of radioactive isotopes of Tc, Ru, Co, Pt and Re and an isonitrile ligand of the formula: (CNX)R, where X is a lower alkyl group having 1 to 4 carbon atoms, wherein R is selected from the group consisting of COOR1 and CONR2R3 where R1 can be H, a pharmaceutically acceptable cation, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, R2, and R3 can be H, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and R2 and R3 can be the same or different is disclosed. Kits that can be used to form these complexes are also disclosed.
申请公布号 AU6330586(A) 申请公布日期 1987.03.24
申请号 AU19860063305 申请日期 1986.08.27
申请人 HARVARD COLLEGE, PRESIDENT AND FELLOWS OF, MASSACHUSETTS;INSTITUTE OF TECHNOLOGY 发明人 ALUN G. JONES;ALAN DAVISON;JAMES KRONAUGE;MICHAEL J. ABRAMS
分类号 C07B59/00;A61K31/28;A61K31/282;A61K33/24;A61K51/00;A61K51/04;C07B31/00;C07C67/00;C07C325/00;C07C395/00;C07F13/00;C07F15/00;C07F15/06 主分类号 C07B59/00
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