摘要 |
Dibenzopyrone derivatives which possess depressant and/or antihypoxia activity are 1,3-bis(dibenzo[b,d]pyranyloxy propanes having the formula (1): <IMAGE> where R and R1 independently represent hydrogen or methyl; where A is <IMAGE> and where X represents single substitution with oxygen or substitution with hydrogen and a second group taken to be hydrogen, hydroxyl, amino, C1-C4 alkylamino or an acyloxy radical <IMAGE> where B represents C1-C15 alkyl, -CH2CH2COOH, or (dimethylamino)phenyl. Also included are pharmaceutically acceptable salt forms of the compounds. These compounds are useful as sedatives and/or for the protection of warm blooded animals from the effects of oxygen deprivation. |