发明名称 INTERLEUKIN -2 WITH EUCARYOTIC BALLAST PORTION )100 AMINO ACIDS>
摘要 Suitable as "ballast portion" for fusion proteins is a part of the amino-acid sequence of interleukin-2 (IL-2) which comprises considerably less than 100 amino acids. It is advantageous to start from a synthetic IL-2 gene which is divided by unique cleavage sites into six segments of which up to three can be linked in any desired sequence by the building block principle. Specific constructions allowing the solubility of the fusion protein to be varied are possible.
申请公布号 AU6676086(A) 申请公布日期 1987.06.25
申请号 AU19860066760 申请日期 1986.12.19
申请人 HOECHST AG 发明人 PAUL HABERMANN
分类号 C12N15/09;A61K35/74;A61K38/00;A61P37/00;C07H21/04;C07K14/00;C07K14/52;C07K14/535;C07K14/54;C07K14/55;C07K14/62;C07K14/815;C07K19/00;C12N1/20;C12N1/21;C12N15/00;C12N15/26;C12P21/02;C12R1/19;C12R1/645 主分类号 C12N15/09
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