| 发明名称 | Oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same | ||
| 摘要 | The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy. | ||
| 申请公布号 | US9522946(B2) | 申请公布日期 | 2016.12.20 |
| 申请号 | US201514748389 | 申请日期 | 2015.06.24 |
| 申请人 | Hanmi Science Co., Ltd. | 发明人 | Jung Sung Youb;Jang Myung Hyun;Shen Ling Ai;Park Young Kyung;Park Young Jin;Kwon Se Chang |
| 分类号 | A61K38/22;C07K14/605;A61P3/04;C07K14/575;A61K38/17;A61K45/06;C07K14/705;A61K38/00 | 主分类号 | A61K38/22 |
| 代理机构 | Baker & Hostetler LLP | 代理人 | Baker & Hostetler LLP |
| 主权项 | 1. A peptide comprising the amino acid sequence of SEQ ID NO:2. | ||
| 地址 | Hawaseong-Si, Gyeonggi-Do KR | ||