发明名称 |
Acetatic abiraterone trifluoroacetate and preparation method and application of same |
摘要 |
Provided are acetaic abiraterone trifluoroacetate, a preparation method and an application of same. The acetaic abiraterone trifluoroacetate is obtained through a salt-forming reaction between acetaic Abiraterone and trifluoroacetic acid. The acetaic abiraterone trifluoroacetate undergoes self-purification through recrystallization, and dissociation and recrystallization are performed on the purified abiraterone acetate trifluoroacetate, so that the obtained acetaic abiraterone has a high purity, a high yield and stable quality, and is capable of meeting the requirement for mass production of acetaic abiraterone. |
申请公布号 |
US9522934(B2) |
申请公布日期 |
2016.12.20 |
申请号 |
US201314409791 |
申请日期 |
2013.02.20 |
申请人 |
Shanghai Cdymax Pharmaceuticals Co., Ltd.;Jiangsu Cdymax Pharmaceuticals Co., Ltd.;Shanghai Acebright Pharmaceuticals Group Co., Ltd. |
发明人 |
An Xiaoxia;Huang Chengjun;Mao Fengwang |
分类号 |
A61K31/4406;C07J43/00;C07C53/10 |
主分类号 |
A61K31/4406 |
代理机构 |
Hamre, Schumann, Mueller & Larson, P.C. |
代理人 |
Hamre, Schumann, Mueller & Larson, P.C. |
主权项 |
1. An abiraterone acetate trifluoroacetate, having the following chemical formula: |
地址 |
Shanghai CN |