PROCESS FOR THE PREPARATION OF A COMPOUND HAVING ANTI- ULCER ACTIVITY

摘要

"PROCESS FOR THE PREPARATION OF A COMPOUND HAVING ANTI ULCER ACTIVITY" of the disclosure The invention refers to processes for the preparation of N-/?/?/?/?-(dimethylamino)methyl?-2-furanyl?methyl?thi?-ethyl?-N'-(3,4-methylenedioxybenzyl)-2-nitro-1,1-ethenedia-mina of formula (I) (I) < IMG > mainly characterized by the reaction of 2-(dimethylaminome-thyl)-5-(R-methyl)furan wherein R represents hydroxy, halogen, dimethylamino or trimethylammonium iodide with 1nitro-2-(3,4-methylenedioxybenzyl)-2-(2-mercaptoetnyl)ethe-nediamine; or with N-(2-mercaptoethyl)-N'-(3,4-methylenedio xybenzyl)urea or thiourea and subsequent reaction of the ob tained intermediate with nitromethane; or also by condensa tion of 2-(dimethylaminomethyl)-5-(2-hydroxy)ethylthiomethyl-furan with 2-amino-2-(3,4-methylenedioxybenzylamino)-1-ni-troethene.