发明名称 Dibenz[be]oxepin-acetic acid derivatives, the preparation thereof and their application in therapy
摘要 Compounds of general formula <IMAGE> in which R1, taken separately, denotes a hydrogen atom or a C1-C4 alkyl group, and R2, taken separately, denotes a hydrogen atom, a C1-C4 alkyl group or a phenylthio or phenylsulphonyl group, or alternatively R1 and R2 together form an ethano bridge or, together with the two carbon atoms 8 and 9, form a fused benzene ring, R3 denotes a hydrogen atom or a methyl group and R4 denotes a hydrogen atom, a C1-C4 alkyl group or a cation of a base which is acceptable in pharmacology, the group CH(R3)COOR4 being at position 2 or 3. have uses in treatment of inflammation, pain and undesirable platelet aggregation.
申请公布号 US4701466(A) 申请公布日期 1987.10.20
申请号 US19860851114 申请日期 1986.04.10
申请人 SYNTHELABO 发明人 PURCELL, THOMAS;ZARD, LYDIA
分类号 A61K31/335;A61P7/02;A61P25/04;A61P29/00;C07D313/12;(IPC1-7):C07D313/12 主分类号 A61K31/335
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