New amino acid salts of carprofen - useful as antiinflammatory agents and analgesics

摘要

Salts (I) of 6-chloro-alpha-methylcarbazole -2-acetic acid (II) with basic alpha-amino acids (III) are new. (II) is in racemic form (carprofen) and (III) is L-lysine or L-arginine. L-lysine rac-6-chloro-alpha -methylcarbazole-2-acetate (Ia) is specifically claimed. USE/ADVANTAGE - (I) are antiinflammatory (antirheumatic) agents and analgesics with higher activity and bioavailability than carprofen.