ISOQUINOLINE DERIVATIVES

摘要

There are provided compounds of the general formula (1) (1) (wherein R1 and R2, which may be the same or different, each represents a hydrogen atom, a hydroxyl group or a group -OP(O) (OH) (OR4) [where R4 represents a hydrogen atom or an alkyl (optionally substituted by a hydroxyl, alkoxy, cyclic ether or cycloalkyl group), alkenyl cycloalkyl, aryl, aralkyl or aroylalkyl group], with the proviso that at least one of R1 and R2 represents a group -OP(O) (OH) (OR4); and R3 represents a hydrogen or halogen atom or a methyl group), and salts thereof. The novel compounds exhibit interesting anti-cancer activity.