发明名称 IMIDAZOLE SUBSTITUTED TRICYCLIC KETONES
摘要 The invention relates to compounds of the general formula (I): <IMAGE> (I) wherein Im represents an imidazolyl group of the formula: <IMAGE> and the various substituents are defined hereinbelow. The compounds are potent and selective antagonists of the effect of 5-HT at 5-HT3 receptors and are useful, for example, in the treatment of psychotic disorders, anxiety, and nausea and vomiting.
申请公布号 AU8184587(A) 申请公布日期 1988.06.02
申请号 AU19870081845 申请日期 1987.11.27
申请人 GLAXO GROUP LTD., 发明人 IAN HAROLD COATES;JOHN BRADSHAW;JAMES ANGUS BELL;DAVID CEDRIC HUMBER;GEORGE BLANCH EWAN;WILLIAM LEONARD MITCHELL
分类号 A61K31/415;C07D403/06 主分类号 A61K31/415
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