发明名称 [(2-substituted 1,2-dihydro-1-oxo-1H-inden-5-yl)oxy]alkanesulfonic acids and salts thereof
摘要 This invention relates to novel [(2-substituted 1,2-dihydro-1-oxo-1H-inden-5-yl)oxy]alkanesulfonic acids and salts thereof. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, the neurological problems caused by AIDS, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydrocephalus, post-operative brain injury trauma, edema due to cerebral infections, various brain concussions, and elevated intracranial pressure.
申请公布号 US4771076(A) 申请公布日期 1988.09.13
申请号 US19870056174 申请日期 1987.06.01
申请人 MERCK & CO., INC. 发明人 CRAGOE, JR., EDWARD J.;PIETRUSZKIEWICZ, ADOLPH M.
分类号 A61K31/12;C07C309/09;(IPC1-7):A61K31/12;C07C143/24 主分类号 A61K31/12
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