发明名称 |
Method for predicting the effectiveness of antineoplastic therapy in individual patients. |
摘要 |
<p>The effectiveness of selected antineoplastic agents may be determined in individual patients by comparing the level of expression of one or more selected growth-regulated genes in neoplastic cells taken from the patient before and shortly after the initiation of therapy. A decrement in expression is prognostic of eventual remission, while a lack of decrement indicates that remission is unlikely. The test may also be accomplished by comparing the level of expression of growth-regulated genes in neoplastic cells in culture before and after incubation of the cells with the selected antineoplastic agents.</p> |
申请公布号 |
EP0341904(A2) |
申请公布日期 |
1989.11.15 |
申请号 |
EP19890304494 |
申请日期 |
1989.05.04 |
申请人 |
TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
GEWIRTZ, ALAN M.;CALABRETTA, BRUNO |
分类号 |
G01N33/15;C12Q1/18;C12Q1/68 |
主分类号 |
G01N33/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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