发明名称 PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AGAINST DISEASES CAUSED BY RETROVIRUS
摘要 The invention relates to the use of amino acid derivatives which inhibit the activity of retroviral proteases and have the structural element of the formula I -NR<1>-CHR<2>-CR<3>-(CHR<4>)n-CO- in which R<1>, R<4>, R<5> and R<6> are each H or alkyl, R<2> is H, alkyl, in each case substituted or unsubstituted aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, het or het-alkyl, R<3> is (H, OH), (H, NR<5>R<6>) or O, het is a 5- or 6-membered N-, S- or O-containing saturated or unsaturated heterocycle and n is 1 or 2, or of the physiologically acceptable salts thereof for treating diseases caused by retroviruses.
申请公布号 HU895215(D0) 申请公布日期 1990.01.28
申请号 HU19890005215 申请日期 1989.10.04
申请人 MERCK PATENT GMBH.,DE 发明人 RADDATZ,PETER,DE;SCHMITGES,CLAUS,DE;HELM,KLAUS E. VON DER ,DE
分类号 A61K31/195;A61K31/33;A61K38/00;A61K38/04;A61K38/55;A61P31/12;A61P31/18 主分类号 A61K31/195
代理机构 代理人
主权项
地址