| 发明名称 |
Factor VIII fusion protein |
| 摘要 |
The present invention relates to modified coagulation factors. In particular, the present invention relates to conjugated Factor VIII molecules fused to a polypeptide such as e.g. an antibody binding protein or a Fc domain. |
| 申请公布号 |
US9493543(B2) |
申请公布日期 |
2016.11.15 |
| 申请号 |
US201113574686 |
申请日期 |
2011.02.10 |
| 申请人 |
Novo Nordisk A/S |
发明人 |
Bolt Gert;Kjaergaard Kristian;Noerby Peder Lisby;Olsen Ole Hvilsted |
| 分类号 |
C07K14/755;A61K38/00 |
主分类号 |
C07K14/755 |
| 代理机构 |
|
代理人 |
Akopyan Nonna G. |
| 主权项 |
1. A fusion protein comprising a Factor VIII (FVIII) molecule and a fusion partner, wherein: (1) the FVIII molecule comprises a heavy chain and a light chain; and (2) the fusion partner is an Fcγ receptor or an immunoglobulin-binding fragment thereof fused to the N-terminus end of the light chain. |
| 地址 |
Bagsvaerd DK |
