发明名称 |
GENETICALLY ENGINEERED PROCESSING OF MICRO-ORGANISM CULTURES AND DNA RELATED THERETO |
摘要 |
In a method of facilitating separation and removal of cellular micro-organisms from a liquid culture medium containing a culture thereof, the cells from which the culture is grown are transformed by a replicable recombinant DNA expression vector having a DNA insert that results in the expression in the transformed micro-organism cells of a product that induces said cells to clump together and form aggregates which at least partially sediment out in the liquid culture medium. The DNA insert may comprise a nucleotide sequence GGAGCCCCAA GGAAAGGGGC CC (SEQ ID NO: 3) corresponding to a human genomic sequence, or modifications thereof in which at least the sequence AAGGAA is retained. Other phenotypic changes may also be produced in the transformed micro-organisms. |
申请公布号 |
WO9010065(A1) |
申请公布日期 |
1990.09.07 |
申请号 |
WO1990GB00337 |
申请日期 |
1990.03.05 |
申请人 |
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED |
发明人 |
HEIGHWAY, JAMES |
分类号 |
C12N1/02;C12N1/21;C12N15/11;C12N15/12;C12N15/70;(IPC1-7):C12N15/12 |
主分类号 |
C12N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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