摘要 |
2063564 9101382 PCTABS00003 There is described a method for assaying the functional activity of free Protein S or Protein C in a plasma sample, by adding to the plasma sample a coagulation enzyme, FIXa, which enzyme promotes the formation of coagulation enzyme FXa optionally together with further coagulation factors, whereafter the sample is incubated and the quantity of thrombin formed from prothrombin, this process being promoted by FXa, is measured in a known manner. The level of functionally active Protein S or Protein C, which is inversely correlated to the amount of thrombin formed, is then determined on the basis of the quantity of thrombin measured, in a known manner with the aid of a standard.
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