摘要 |
The invention relates to pyridazine derivatives of formula : (I) in which : -Ar represents a phenyl group substituted by R1 and R2 or a heterocyclic radical such as a pyridyl group, unsubstituted or substituted by methyl or methoxy, or a thienyl group, unsubstituted or substituted by chlorine, methyl or methoxy ; -R1 and R2 each independently denotes hydrogen, halogen, trifluoromethyl, hydroxyl, C1-C4 alkoxy or C1-C4 alkyl ; -R3 represents linear or branched C1-C4 alkyl, C3-C7 cycloalkyl, benzyl, phenethyl or the Ar' radical, Ar' being phenyl substituted by R1 and R2 ; -R4 represents : a group, with n = 0 or 1 in which X1 represents hydrogen or methyl ; -R5 represents a C1-C6 linear alkyl group ; -R6 represents a C1-C6 linear alkyl group, or R5 and R6 also constitute with the nitrogen atom to which they are attached a heterocycle selected from morpholine, pyrrolidine or piperidine ; as well as its salts with mineral or organic acids. The above compounds are useful as drugs, notably as drugs active on the cholinergic receptors of type M1.
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