发明名称 |
Process for the preparation of (-) (2R,3S)-2,3-epoxy-3-(4-methoxyphenyl) propionic acid methylester and its enantiomer. |
摘要 |
<p>Process for the preparation of methyl (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)propionate, characterised in that a solution of a mixture of enantiomers of trans methyl (+/-)-2,3-epoxy-3-(4-methoxyphenyl)propionate, rich in laevorotatory enantiomer, is prepared first of all and then a crystal seed of laevorotatory enantiomer is then added to the solution, which is allowed to crystallise, and the crystals formed are isolated.</p> |
申请公布号 |
EP0453330(A1) |
申请公布日期 |
1991.10.23 |
申请号 |
EP19910400586 |
申请日期 |
1991.03.04 |
申请人 |
SYNTHELABO |
发明人 |
ZARD, LYDIA;TIXIDRE ARLETTE;ROSSEY, GUY;WICK, ALEXANDER |
分类号 |
C07B57/00;C07D301/32;C07D303/48 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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