发明名称 AMPHIPHILIC FLUORINE DERIVATIVES WITH TELOMERIC STRUCTURES; PREPARATION AND BIOMEDICAL APPLICATIONS
摘要 <p>New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having formula (I), wherein RF is a fluorinated radical, X is a linear or branched alkylene, R1 is H or CH¿3, R?2 is a radical having at least one OH group, R3 is a radical derived from an amino acid or a peptide, 1 « n « 50 and 0 « m « 200 with 0.2 « n/n+m « 1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.</p>
申请公布号 WO1992002560(A1) 申请公布日期 1992.02.20
申请号 EP1991001521 申请日期 1991.08.08
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