发明名称 |
A METHOD FOR THE PRODUCTION OF POTASSIUM SALT OF N-SUBSTITUTED-1-ALKYLTHIO-2-NITROETHENAMINE |
摘要 |
<p>A potassium salt useful in the production of N-substituted-1-alkylthio-2-nitroethenamines is produced by the reaction of the dipotassium salt of nitrodithioacetic acid with certain straight chain alkylamines, thereby converting only one of the KS-groups to an alkylamine group. The resulting monopotassium salt may be alkylated to produce the required N-substituted-1-alkylthio compound which may be reacted with a suitable amine to produce the histamine H2-antagonist ranitidine.</p> |
申请公布号 |
IN170319(B) |
申请公布日期 |
1992.03.14 |
申请号 |
IN1990MA24719 |
申请日期 |
1990.04.04 |
申请人 |
GLAXO GROUP LTD. |
发明人 |
JAMES IAN GRAYSON;GRAHAM HEYES;ARTHUR JACKSON;PAUL EDWARD ROWNEY |
分类号 |
C07D307/52;B01J35/12;C07B61/00;C07C319/14;C07C319/22;C07C323/24;C07C323/27;C07D307/38;C07D317/58;C07D407/12;(IPC1-7):C07C149/14 |
主分类号 |
C07D307/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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