| 发明名称 |
ISOLATION OF AN Mr 52,000 FK506 BINDING PROTEIN AND MOLECULAR CLONING OF A CORRESPONDING HUMAN cDNA |
| 摘要 |
An FK506 binding protein of mammalian origin of approximate size (Mr) 52,000, isolated by FK506 affinity chromatography and a corresponding human cDNA of approximate size 2.2 Kb, isolated by screening a human placenta cDNA library with a DNA probe whose sequence predicts a consensus amino acid sequence present in five FKBP12 sequences and in the human FKBP13 sequence. |
| 申请公布号 |
WO9307269(A1) |
申请公布日期 |
1993.04.15 |
| 申请号 |
WO1992US08667 |
申请日期 |
1992.10.09 |
| 申请人 |
VERTEX PHARMACEUTICALS, INC. |
发明人 |
PEATTIE, DEBRA, A.;HARDING, MATTHEW, W.;LIVINGSTON, DAVID, J. |
| 分类号 |
C07K14/72;C12N9/90;C12N15/12 |
主分类号 |
C07K14/72 |
| 代理机构 |
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