| 发明名称 |
SUBSTANCE WITH INTERLEUKIN-8 INHIBITING ACTIVITY AND PROCESS FOR ITS PREPARATION |
| 摘要 |
A substance is prepared having interleukin-8 inhibiting activity by extracting psoriatic scales and separating the extract on several successive HPLC columns, using an assay for IL-8i activity based on the inhibition of myeloperoxidase release and/or of the neutrophil chemotaxis of a reference sample. The substance is suitable for the preparation of anti-inflammatory medicines.
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| 申请公布号 |
US5234911(A) |
申请公布日期 |
1993.08.10 |
| 申请号 |
US19910642119 |
申请日期 |
1991.01.16 |
| 申请人 |
GIST-BROCADES, N.V. |
发明人 |
CHRISTOPHERS, ENNO;SCHROEDER, JENS-MICHAEL |
| 分类号 |
A61K38/00;A61P11/00;A61P29/00;A61P37/08;C07K1/16;C07K14/435;C07K14/47;C07K14/52;C07K14/54;C12N1/21;C12N15/19;C12P21/00;C12R1/125;C12R1/19 |
主分类号 |
A61K38/00 |
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