发明名称 Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents.
摘要 <p>Aryl-fused- and hetaryl-fused-2,4-diazepines of formula XXXVI, &lt;CHEM&gt; wherein A is an aryl, cycloalkyl or hetaryl or substituted aryl ring R&lt;1&gt; is hydrogen, alkyl, aralkyl, aryl, hetaryl or substituted aryl; R&lt;2&gt; is hydrogen, alkyl, aralkyl, aryl or substituted alkyl or aryl; R&lt;3&gt; is alkyl, aryl, aralkyl, hetaryl or heteroatom substituted alkyl, aryl, aralkyl or hetaryl; R&lt;4&gt; is hydrogen, alkyl or substituted alkyl; R&lt;5&gt; is hydrogen, alkyl, aryl, aralkyl, hetaryl or substituted aryl, pharmaceutical compositions containing these and methods of treating cardiac arrhythmia with the compounds of formula XXXVI are disclosed.</p>
申请公布号 EP0597540(A1) 申请公布日期 1994.05.18
申请号 EP19930203115 申请日期 1993.11.06
申请人 STERLING WINTHROP INC. 发明人 JOHNSON, ROBERT ED., C/O STERLING WINTHROP INC.;SCHLEGEL, DONALD CHARLES., C/O STERLING WIN. INC.;EZRIN, ALAN MARK., C/O STERLING WINTHROP INC.
分类号 C07D237/32;A61K31/55;A61K31/395;A61P9/06;C07D243/00;C07D243/04;C07D245/04;C07D245/06;C07D401/04;C07D401/06;C07D403/06;C07D405/04;C07D405/06;C07D405/12;C07D409/04;C07D409/06;C07D471/04;C07D487/04;C07D491/048;C07D495/04;(IPC1-7):C07D243/04;C07D413/06 主分类号 C07D237/32
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