T-cell receptor specific for antigen polypeptides and related polynucleotides

摘要

Oligonucleotide sequences are provided coding for T-cell-specific antigen receptors or fragments thereof. The oligonucleotide sequences can be used as probes for detecting helper and cytotoxic T-cells, preparing and isolating DNA sequences encoding for the receptor polypeptide, and in constructions for expression of receptor polypeptides or fragments thereof. In addition, processing signals from the receptor subunits can be employed in conjunction with modified wild type oligonucleotide sequences or non-wild type oligonucleotide sequences. TM86 was deposited at the A.T.C.C. on Mar. 1, 1984 and given Accession No. 40099. TT11 was deposited at the A.T.C.C. on Oct. 22, 1984 and given Accession No. 40141.