发明名称 |
Use of pyrimidine 3-oxide derivatives for slowing down hair loss and topical compositions used |
摘要 |
PCT No. PCT/FR91/00596 Sec. 371 Date Jan. 19, 1993 Sec. 102(e) Date Jan. 19, 1993 PCT Filed Jul. 19, 1991 PCT Pub. No. WO92/01437 PCT Pub. Date Feb. 6, 1992.Pyrimidine 3-oxide derivatives and their use for the treatment of hair loss. The compositions contain in a physiologically acceptable medium at least one compound corresponding to the formula (I): <IMAGE> (I) in which: R1 denotes a methyl or NHR4 group in which R4 denotes a C1-C4 alkyl group or hydrogen; R2 denotes hydrogen or a group NHR4 in which R4 has the same meaning as above; R2 may also denote methyl when R1 denotes methyl; when R1 denotes NH2, R2 cannot be hydrogen; R3 may denote a hydrogen atom or a C1-C4 alkyl group which may optionally carry; a group OR5 in which R5 denotes a C1-C4 alkyl group, a benzene nucleus which is optionally substituted by one or more C1-C4 alkoxy groups; R3 may also denote a halogen atom or a nitro or amino group; and the physiologically acceptable acid addition salts.
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申请公布号 |
US5328914(A) |
申请公布日期 |
1994.07.12 |
申请号 |
US19930956507 |
申请日期 |
1993.01.19 |
申请人 |
L'OREAL |
发明人 |
HOCQUAUX, MICHEL;DUMATS, JACQUELINE;GALEY, JEAN B. |
分类号 |
A61K8/00;A01N43/54;A61K8/04;A61K8/33;A61K8/34;A61K8/36;A61K8/362;A61K8/365;A61K8/368;A61K8/39;A61K8/40;A61K8/44;A61K8/46;A61K8/49;A61K8/73;A61K8/86;A61K31/505;A61P17/14;A61Q5/00;A61Q5/02;A61Q7/00;C07C65/40;C07C233/47;C07D213/80;C07D239/26;C07D239/34;C07D239/42;C07D239/46;C07D239/48;C07D239/50;C07D239/52;(IPC1-7):A61K7/06 |
主分类号 |
A61K8/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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