发明名称 |
Heteroaryl quinolines as inhibitors of leukotriene biosynthesis |
摘要 |
Compounds having the formula I: <IMAGE> I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
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申请公布号 |
US5410054(A) |
申请公布日期 |
1995.04.25 |
申请号 |
US19930095131 |
申请日期 |
1993.07.20 |
申请人 |
MERCK FROSST CANADA, INC. |
发明人 |
FRIESEN, RICK;YOUNG, ROBERT N.;GIRARD, YVES;BLOUIN, MARC;DUBE, DANIEL |
分类号 |
C07D405/12;C07D405/14;C07D409/14;C07D417/14;C07D493/08;(IPC1-7):C07D215/12;C07D215/16;C07D217/22;C07D217/18 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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