发明名称 Method for treating and inhibiting gastric and duodenal ulcers
摘要 A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the following formula (I): (NeuAc- alpha (2-3)-pGal- beta (1)-(-X-)m-(-Y-)n-)p-Z wherein X is a chemical bond or a group capable of linking the p galactose to either the linking group Y or the multivalent support Z; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C; Y is a linking group; Z is a multivalent support; m is 0 or 1; n is 0 or 1; and p is an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the formula (II): NeuAc- alpha (2-3)-pGal- beta (1)-A wherein A is a group capable of bonding to the p galactose; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C.
申请公布号 AU1932395(A) 申请公布日期 1995.09.18
申请号 AU19950019323 申请日期 1995.03.02
申请人 NEOSE PHARMACEUTICALS, INC. 发明人 DAVID A ZOPF;PAUL M SIMON;STEPHEN ROTH;EDWARD J MCGUIRE;DENNIS H LANGER
分类号 C07H13/06;A61K31/70;A61K31/7012;A61K31/702;A61K31/7024;A61K45/06;A61K47/48;A61P1/04;A61P31/04;C07H7/027 主分类号 C07H13/06
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