发明名称 |
CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL USES THEREOF |
摘要 |
There is provided compounds of formula (I), wherein E1, E2, E3, E4, L1, Y1, Y2, Y3, Ra and z have meanings provided in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of respiratory diseases and inflammation. |
申请公布号 |
WO2016177845(A1) |
申请公布日期 |
2016.11.10 |
申请号 |
WO2016EP60110 |
申请日期 |
2016.05.04 |
申请人 |
ASTRAZENECA AB |
发明人 |
RONN, Robert;LINDH, Carl, Jonas;RINGBERG, Erik;ANDERSSON, Hanna, Birgitta, Ellinor;NILSSON, Peter;SCHAAL, Wesley, Ralph;MUNCK AF ROSENSCHÖLD, Magnus;NIKITIDIS, Antonios;NIKITIDIS, Grigorios;JOHANNESSON, Petra;TYRCHAN, Christian |
分类号 |
C07D213/74;A61K31/44;A61K31/4439;A61K31/496;A61K31/505;A61P11/00;A61P29/00;C07D239/42;C07D241/20;C07D401/08 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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