发明名称 Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides.
摘要 <p>Certain enol ethers and esters of the formula <CHEM> where X and Y are each hydrogen, fluoro or chloro; R<1> is 2-thienyl or benzyl and R is alkanoyl, cycloalkylcarbonyl, phenylalkanoyl, chlorobenzoyl, methoxybenzyl, phenyl, thenoyl, omega-alkoxycarbonylalkanoyl, alkoxycarbonyl, phenoxycarbonyl, 1-alkoxyalkyl, 1-alkoxycarbonyloxyalkyl, alkyl, alkylsulfonyl, methylphenylsulfonyl or dialkylphosphonate are useful as prodrug forms the known 3-acyl-2-oxindole-1-carboxamide antiinflammatory and analgesic agents.</p>
申请公布号 GR3017565(T3) 申请公布日期 1995.12.31
申请号 GR19950402678T 申请日期 1995.09.28
申请人 PFIZER INC. 发明人 CRAWFORD, THOMAS CHARLES;REITER, LAWRENCE ALAN
分类号 C07D209/34;C07D409/06;(IPC1-7):C07D209/34;A61K31/40 主分类号 C07D209/34
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