| 摘要 |
A protein having potent anti-retrovirus activity is obtained by a method which comprises culturing a strain of CD4-positive T cells, such as a subclone of CEM cells designated 4084, in a tissue culture medium under conditions in which the cells are induced to produce and secrete a protein having anti-retrovirus activity, separating the cells from the culture medium containing the protein and then recovering the protein from the medium. A protein in the medium having anti-retrovirus activity has a molecular weight of at least 30,000 daltons as determined by passing the medium through a membrane with defined pore size that retains molecules of 30,000 daltons. |
