发明名称 |
FLUOROALKYL/ALKENYL-SUBSTITUTED BENZOYLGUANIDINES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC, AND MEDICAMENT CONTAINING THEM |
摘要 |
Fluoroalkyl/alkenyl-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them There are described benzoylguanidines of the formula I I <IMG> having the definitions of R(1) to R(4) indicated in the text, and their pharmaceutically tolerable salts. They are obtained by reaction of a compound II (II) <IMG> with guanidine. They are outstanding agents for the treatment of disorders of the cardiovascular system.
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申请公布号 |
CA2157856(A1) |
申请公布日期 |
1996.03.10 |
申请号 |
CA19952157856 |
申请日期 |
1995.09.08 |
申请人 |
HOECHST AKTINGESELLSCHAFT |
发明人 |
WEICHERT, ANDREAS;KLEEMANN, HEINZ-WERNER;LANG, HANS-JOCHEN;SCHWARK, JAN-ROBERT;ALBUS, UDO;SCHOLZ, WOLFGANG |
分类号 |
A61K31/165;A61K31/155;A61K31/18;A61K31/275;A61P3/08;A61P3/10;A61P9/00;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P13/02;A61P15/00;A61P25/00;A61P25/02;A61P35/00;A61P41/00;A61P43/00;C07C277/08;C07C279/22;C07C311/29;C07C311/38;C07C317/44;C07C323/62;(IPC1-7):C07C279/22;C07D215/14;C07D217/16;A61K31/16;C07D333/24;C07C317/32;A61K31/33;C07D207/337;C07C323/44;C07C311/47;C07D213/58 |
主分类号 |
A61K31/165 |
代理机构 |
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地址 |
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