发明名称 |
NEUE VERBINDUNGEN, ''LEUSSTRODUCSINS'' GENNANT, IHRE HERSTELLUNG UND THERAPEUTISCHE VERWENDUNGEN |
摘要 |
New compounds, which we have named the "Leustroducsins" have the formula (I): <CHEM> in which R represents a 5-methylhexanoyloxy group, a 6-methyloctanoyloxy group or a 7-methyloctanoyloxy group, and salts thereof, and may be prepared by fermentation using a microorganism of the genus Streptomyces, especially a strain of the species Streptomyces platensis, such as strain SANK 60191 (FERM BP-3288). These compounds may be used for the treatment or prophylaxis of: adverse reactions resulting from cancer chemotherapy or radiotherapy; infections; cancer; cerebral dysfunction; and fungal infections. |
申请公布号 |
AT134640(T) |
申请公布日期 |
1996.03.15 |
申请号 |
AT19920302718T |
申请日期 |
1992.03.27 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
KOMAHA, TAKAFUMI,C/O SANKYO COMPANY LT;KANEKO, ISAO,C/O SANKYO COMPANY LTD.;NAKAMURA, TAKEMICHI,C/O SANKYO COMPANY;MATSUDA, KEIICHI,C/O SANKYO COMPANY LT;KAGASAKI, TAKESHI,C/O SANKYO COMPANY L;OHTSURUGI, IZUMI-CHO;ENOKITA, RYUZO,C/O SANKYO COMPANY LTD. |
分类号 |
C07D309/38;A61K31/655;A61K31/665;A61P7/00;A61P31/10;C07F9/117;C07F9/655;C12N1/14;C12P9/00;C12P17/06;C12R1/465;(IPC1-7):C07F9/655 |
主分类号 |
C07D309/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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