摘要 |
N-phenylalkyl substituted alpha -amino carboxamide derivatives of formula (I) <IMAGE> (I) wherein R is C1-C8 alkyl, C3-C8 cycloalkyl, furyl, thienyl, pyridyl or unsubstituted or substituted phenyl; A is a -(CH2)m- or -(CH2)p-X-(CH2)q- group wherein X is -O-, -S- or -NR4-; R1, R2, R3, R'3, R4, n, m, p and q are as herein defined; and each of R5 and R6 is independently hydrogen or C1-C6 alkyl, and the pharmaceutically acceptable salts thereof, are active on the central nervous system and can be used as anti-epileptic, anti-Parkinson, neuroprotective, antidepressant, antispastic and/or hypnotic agents in mammals.
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申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
DOSTERT, PHILIPPE;PEVARELLO, PAOLO;HEIDEMPERGHER, FRANCO;VARASI, MARIO;BONSIGNORI, ALBERTO;RONCUCCI, ROMEO |