| 摘要 |
A method for immunizing mammals, particularly humans, against atherosclerosis, and pharmaceutical preparations for the prophylaxis and treatment of atherosclerosis. The pharmaceutical preparations are obtained by subjecting certain lipoproteins, derived from either the blood of the patient or from the same mammalian species, to an in vitro fusion step to provide heavy microemulsion particles. The fused proteins are then incorporated into a pharmaceutically acceptable immunization carrier or diluent for delivery to the patient. These compositions avoid the complexities of presently available methods of treatment, and appear to be more effective. The lipoproteins used are those known as VLDL, LDL, and VLDL-remnant or IDL.
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