| 发明名称 |
DNA methyltransferase antisense oligonucleotides |
| 摘要 |
The invention encompasses tumorigenicity-inhibiting antisense oligonucleotide sequences complementary to mRNA or double-stranded DNA that encodes mammalian DNA methyl transferase. It further encompasses methods for inhibiting tumorigenicity and pharmaceutical composition comprises the tumorigenicity-inhibiting antisense nucleotide.
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| 申请公布号 |
US5578716(A) |
申请公布日期 |
1996.11.26 |
| 申请号 |
US19930161673 |
申请日期 |
1993.12.01 |
| 申请人 |
MCGILL UNIVERSITY;HYBRIDON, INC. |
发明人 |
SZYF, MOSHE;VON HOFE, ERIC |
| 分类号 |
C12N15/09;A61K31/70;A61P35/00;C07H21/04;C12N15/113;(IPC1-7):C07H21/00;A61K48/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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