ESTERS AND AMIDES AS PLA2 INHIBITORS

摘要

The present invention relates to a novel fatty acid derivative of formula (I), wherein R<1> is acyl group; R<2> is acyl(lower)alkyl; R<3> is hydrogen, aryl(lower)alkyl, etc.; R<4> is acyl(lower)alkyl; and X is -O-, -NH- or formula (II) [wherein R<5> is lower alkyl, etc.]; and a pharmaceutically acceptable salt thereof, which is useful as a medicament; the processes for the preparation of said fatty acid derivative or a salt thereof; a pharmaceutical composition comprising said fatty acid derivative or a pharmaceutically acceptable salt thereof; etc.