FORMULATIONS OF BENDAMUSTINE

摘要

Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter administration time without the active ingredient coming out of solution as compared to presently available formulations.

主权项

1. A method of treating chronic lymphocytic leukemia or indolent B cell non-Hodgkin's lymphoma in a subject comprising parenterally administering to the subject a volume of about 100 mL or less of a liquid composition comprising
bendamustine, or a pharmaceutically acceptable salt thereof; a polar aprotic solvent; and a parenterally acceptable diluent;over a period of less than or equal to about 15 minutes.