发明名称 |
NOVEL SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL |
摘要 |
Novel substituted [2-(1-piperazinyl)ethoxy]methyl compounds of formula (I), wherein R1 is a -CONH2, -CN, -COOH, -COOM or -COOR3 group, where M is an alkali metal, R3 is a C1-4 alkyl radical; and R2 is a hydrogen atom or a -COR4 or -R5 group where R4 is selected from -OR6 or -R7 groups, wherein R5 is an allyl or alkylaryl radical, R6 is a straight or branched C1-4 alkyl radical, a haloalkyl radical, alkylaryl, alkylnitroaryl or alkylhaloaryl, and R7 is haloalkyl; a method for preparing said compounds, as well as the use thereof for preparing compounds that are themselves valuable intermediates for the preparation of 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid or 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid and/or pharmaceutically acceptable salts thereof, are disclosed.
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申请公布号 |
WO9737982(A1) |
申请公布日期 |
1997.10.16 |
申请号 |
WO1997BE00038 |
申请日期 |
1997.03.28 |
申请人 |
UCB S.A.;DUCHENE, GUY;DELEERS, MICHEL;BODSON, GUY;MOTTE, GENEVIEVE;LURQUIN, FRANCOISE |
发明人 |
DUCHENE, GUY;DELEERS, MICHEL;BODSON, GUY;MOTTE, GENEVIEVE;LURQUIN, FRANCOISE |
分类号 |
C07D295/14;C07D295/08;C07D295/088;C07D295/16;C07D295/20;C07D295/205;(IPC1-7):C07D295/08 |
主分类号 |
C07D295/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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