METHODS OF TREATING IMMUNOPATHOLOGIES USING POLYUNSATURATED FATTYACIDS

摘要

The present invention provides methods of treating a range of T-cell mediated disease states in a subject. The methods involve administering to the subject a composition comprising a therapeutically effective amount of a polyunsaturated fatty acid and a pharmaceutically acceptable carrier; in which the plyunsaturated fatty acid contains 18-25 carbons, 1-6 double bonds and has one or two substitutions selected from the group consisting of beta oxa, gamma oxa, beta thia and gamma thia, or the polyunsaturated fatty acid contains 16-26 carbon chain, 3-6 double bonds and is covalently coupled at the carbolxylic acid group to an amino acid.