发明名称 Cryopreservation and extensive subculturing of human mesenchymal stem cells
摘要 Disclosed is a cryopreserved preparation of an isolated, homogeneous population of viable human mesenchymal stem cells obtained from periosteum, bone marrow, cord blood, peripheral blood, dermis, muscle, or other known sources of mesenchymal stem cells. After restoration from cryopreservation, the human mesenchymal stem cells can differentiate into cells of connective tissue types, including bone, cartilage, adipose, tendon, ligament, muscle, dermis, and marrow stromal connective tissue which supports the differentiation of hematopoietic stem cells. The cryopreserved preparation of human mesenchymal stem cells binds to antibodies produced from hybridoma cell lines SH2, SH3, and SH4, which have the ATCC accession numbers HB 10743, GB 10744, and HB 10745, respectively.
申请公布号 AU2730497(A) 申请公布日期 1997.11.07
申请号 AU19970027304 申请日期 1997.04.15
申请人 OSIRIS THERAPEUTICS, INC.;CASE WESTERN RESERVE UNIVERSITY 发明人 SCOTT P BRUDER;NEELAM JAISWAL;STEPHEN E HAYNESWORTH
分类号 A61K35/12;C12N5/0775 主分类号 A61K35/12
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