发明名称 |
Use of a modified rev-responsive element (rre) in methods and compositions for combatting hiv infection |
摘要 |
The invention relates to an isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, the sites comprising a nucleation motif and an oligomerization motif, wherein the nucleic acid binds Rev protein monomers with a higher degree of co-operativity than wild-type RRE. |
申请公布号 |
AU2572097(A) |
申请公布日期 |
1997.11.07 |
申请号 |
AU19970025720 |
申请日期 |
1997.04.15 |
申请人 |
THEREXSYS LIMITED |
发明人 |
JONATHAN KARN;RODNEY WARREN ZEMMEL;PETER JONATHAN GASKING BUTLER;ROGER KINGDON CRAIG;ALISTAIR SIMPSON IRVINE |
分类号 |
G01N33/50;A61K31/7088;A61K38/00;A61K48/00;A61P31/18;A61P37/04;C07H21/00;C07K14/155;C07K14/16;C12N5/10;C12N15/09;C12N15/49;G01N33/15;G01N33/566 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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