发明名称 |
Detection of isoniazid resistant strains of M. tuberculosis |
摘要 |
A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction length polymorphism analysis to determine whether or not the DNA of said strain has an NciI-MspI restriction site at the codon corresponding to codon 463 of an M. tuberculosis katG gene consensus sequence.
|
申请公布号 |
US5688639(A) |
申请公布日期 |
1997.11.18 |
申请号 |
US19940228662 |
申请日期 |
1994.04.18 |
申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH |
发明人 |
COCKERILL, FRANKLIN R.;KLINE, BRUCE C.;UHL, JAMES R. |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C07H21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|