BIOLOGICALLY ACTIVE PHOSPHOTRIESTER-TYPE COMPOUNDS

摘要

Compounds of formula RS-P(=O) (QR)-Nu where: R is a radical -(CH2)n-W-X; X is a radical -C(=Z) (Y) or -S-U; Z is O or S; W is O or S; Q is O or S; Y and U are an alkyl, aryl or saccharide radical which is optionally substituted with, for example, an OH, SH or NH group; n is equal to 1 to 4, preferably 1 or 2; and Nu is a radical consisting of a residue of a biologically active compound or the dephosphorylated residue of a compound which is biologically active when it bears a phosphate or phosphonate group.