发明名称 |
METHOD OF TREATMENT OF HUMAN WITH IMMUNOSUPPRESSION AT SEPSIS |
摘要 |
FIELD: medicine, infectious diseases. SUBSTANCE: invention proposes the use of human interleukin-2 prepared from yeast Saccharomyces cerevisiae. Strain is deposited in All-Russian Collection of industrial microorganisms at N VKPM-U 791. Interleukin-2 is administrated at doses from 100 000 to 3 000 000 IU/24 h/1 m patient body surface. In contrast to other interleukins used for treatment of sepsis the proposed interleukin-2 shows stimulating effect on "resting" lymphocytes, induces production of interleukin-8 and tumor necrosis factor. Method can be used for treatment of severe states in human caused by infection and for correction of IMMUNOSUPPRESSION at sepsis in human also. EFFECT: enhanced effectiveness of treatment. 5 tbli
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申请公布号 |
RU2115428(C1) |
申请公布日期 |
1998.07.20 |
申请号 |
RU19950104171 |
申请日期 |
1995.03.28 |
申请人 |
TOVARISHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "BIOTEKH" |
发明人 |
TSIBIN JU.N.;GROMOV M.I.;PIVOVAROVA L.P.;RAZUMOVA N.K.;TARELKINA M.N.;MASIJANSKAJA T.I.;SHIROKOV D.M.;BUBNOVA N.A.;TONEH R.V.;SHLJAPNIKOV S.A.;SMIRNOV M.N.;KHROMOV-BORISOV N.N. |
分类号 |
A61K38/20;A61K35/26;(IPC1-7):A61K38/20 |
主分类号 |
A61K38/20 |
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