发明名称 |
N-oxides of heterocyclic esters, amides, thioesters, and ketones |
摘要 |
This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity. |
申请公布号 |
AU6181598(A) |
申请公布日期 |
1998.09.18 |
申请号 |
AU19980061815 |
申请日期 |
1998.02.26 |
申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
GREGORY S. HAMILTON;JOSEPH P. STEINER;ERIC S. BURAK |
分类号 |
A61K31/44;A61K31/4427;A61K31/47;A61P25/00;A61P25/28;A61P43/00;C07D401/12 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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