发明名称 |
Pharmaceutical formulations containing poorly soluble drug substances |
摘要 |
This invention provides solid pharmaceutical dispersions comprising a poorly soluble drug substance, as SR48692 or naproxen, xylitol and Transcutol, and a method of preparing such dispersions comprising the steps of dissolving the poorly soluble drug substance in Transcutol and adding the solution to xylitol. The dispersions exhibit good pharmaceutical properties and reduced levels of impurities and degradation products. |
申请公布号 |
ZA9801775(B) |
申请公布日期 |
1998.10.19 |
申请号 |
ZA19980001775 |
申请日期 |
1998.03.03 |
申请人 |
SANOFI PHARMACEUTICALS, INC. |
发明人 |
WILLIAM L. ROCCO;SHARON M. LAUGHLIN;NANCY M. FRANSON |
分类号 |
A61K9/20;A61K31/00;A61K31/192;A61K31/4709 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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