Xanthine derivatives.

摘要

There is provided a novel xanthine Compound(I) wherein R<1> and R<2> are the same or different and each represent hydroxy-substituted, oxo-substituted or unsubstituted lower alkyl, Y is a single bond or alkylene, and Q is wherein R<3> and R<4> are the same or different and each represent hydrogen or hydroxy, n is 0 or 1; provided that when both of R<3> and R<4> are hydrogen, at least one of R<1> and R<2> is hydroxy-substituted or oxo-substituted lower alkyl; or a pharmaceutically acceptable salt thereof. The xanthine compound has adenosine A1 receptor antagonizing activity, and thus shows diuretic effect, renal-protecting effect, bronchodilatory effect, cerebral function improving effect and anti-dementia effect.