| 发明名称 |
TUMOUR SUPPRESSOR GENE DBCCR1 AT 9q32-33 |
| 摘要 |
The application relates to the identification of a tumour suppressor locus at 9q32-33, and a gene within this region is disclosed. The gene is called "DBCCR1" for <u>D</u>eleted in <u>B</u>ladder <u>C</u>ancer <u>C</u>hromosome <u>R</u>egion candidate 1. The application further relates to uses of these findings, in particular in the diagnostic, prophylactic and therapeutic treatment of cancer, especially bladder cancer. In particular, some forms of cancer are linked to hypermethylation based silencing of the DBCCR1 promoter or gene.
|
| 申请公布号 |
WO9854318(A1) |
申请公布日期 |
1998.12.03 |
| 申请号 |
WO1998GB01515 |
申请日期 |
1998.05.26 |
| 申请人 |
MARIE CURIE RESEARCH INSTITUTE;KNOWLES, MARGARET;HABUCHI, TOMONORI |
发明人 |
KNOWLES, MARGARET;HABUCHI, TOMONORI |
| 分类号 |
G01N33/53;A61K35/76;A61K38/00;A61K48/00;A61P1/00;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P35/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12Q1/68;(IPC1-7):C12N15/12;C07K14/74;C12N15/86;C07K16/22;A61K31/70 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
