摘要 |
The pyrrolidine dione derivatives, for use as an inhibitor of retinoic acid metabolism, have general formula (I), in which R<1> is hydrogen or an alkyl, cycloalkyl or aralkyl goup; each of R<2> and R<3> is independently hydrogen or an alkyl, cycloalkyl or aryl group; and each of x and y is independently zero or one; wherein at least one of R<1>, R<2> and R<3> has at least five carbon atoms or a pharmaceutically acceptable salt of said pyrrolidine dione. |